TrinCE presents LumiPore, a platform for cell transfection by photoporation. This transmissiong and fluorescent imaging device can insert functional molecules into single cells by using laser light technology. This technology, initially developed by Lambda-X for space application, will now be used in a bench-top photoporator for Ghent University. This photoporator generates nano-sized pores in the membrane of eukaryotic cells. Combining the technology of Lambda-X and Ghent University has created interesting applications in the fields of tissue engineering and basic cell research, open for other applications.
We received support in the development of a photoporation device, a system for cell therapy production. Verhaert, the ESA technology transfer broker, supported UGhent in the transfer process of the space technology developed in the context of the AMME project, wherein a compact dedicated confocal laser scanning microscope (CLSM) has been developed for 3D fluorescence imaging of biological samples. Combining our laser based transfection technology with this imaging technology originally developed for space enables automated delivery of large molecules into single cells in complex environments.
Dr. Stephan Stremersch
Laboratory for General Biochemistry and Physical Pharmacy, Ghent University